Clinical Guide to Probiotic Products Available in USA
Applications, Dosage Forms and Clinical Evidence to Date -
2024 Edition
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Application (select all that apply with ctrl+click)
AAD - Antibiotic associated diarrhea - Prevention
BG - Reduces blood glucose in Type II Diabetes (postprandial BG)
C - Constipation
CDAD - Clostridium difficile associated diarrhea - Prevention
CID - Common infectious disease - community acquired
FAP - Functional abdominal pain
GDM - Gestational Diabetes Mellitus (GDM) prevention - in conjunction with nutritional counseling
HP - Helicobacter pylori - Adjunct to standard eradication therapy
IBD-P - Inflammatory bowel disease - Pouchitis
IBD-UC - IBD - Ulcerative colitis - Adjunct to standard therapy
IBS - Irritable bowel syndrome
ID - Infectious diarrhea
LDL-C - Reduces LDL and total cholesterol
LH - Liver Health (NASH/NAFLD/MHE; as adjunct to standard therapy; see studies for specific population)
M/A - Mood and Affect (symptoms related to stress/anxiety; not a substitute for standard treatment)
Mastitis - Mastitis in breastfeeding mothers (treatment and prevention)
MP - Migraine prevention (reduction of frequency and severity)
OH - Oral health (reductions of tonsillitis, laryngitis, and dental caries)
SA/R - Mild-Moderate Seasonal Allergies/Rhinitis
TD - Traveler’s diarrhea prevention
WM - Weight Management (aids in reduction of body weight, body fat mass and waist circumference)
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Introduction
Adult Health
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Functional Foods
References
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REFERENCES
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1
Eskesen, D. et al. "Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial" British Journal of Nutrition (2015), 114, 1638–1646
2
Brenner, DM, and WD Chey. "Bifidobacterium Infantis 35624: A Novel Probiotic for the Treatment of IBS." Reviews in Gastroenterological Disorders 9.1 (2009): 7-15.
3
Quigley, EM, PJ Whorwell, L. Altringer, J. Morel, L. O'Mahony, and F. Shanahan. "Probiotic Use Results in Normalization of Bowel Movement Frequency in IBS. Results from a Clinical Trial with the Novel Probiotic Bifidobacterium Infantis 35624." American Journal of Gastroenterology 100.S9 (2005): S326.
4
Whorwell, P., L. Altringer, J. Morel, Y. Bond, D. Charbonneau, L. O'Mahony, B. Kiely, F. Shanahan, and EM Quigley. "Efficacy of an Encapsulated Probiotic Bifidobacterium Infantis 35624 in Women with Irritable Bowel Syndrome." American Journal of Gastroenterology 101 (2006): 1581-590.
5
O'Mahony, L., J. Mccarthy, P. Kelly, G. Hurley, F. Luo, K. Chen, G. C. O'Sullivan, B. Kiely, J. K. Collins, F. Shanahan, and E. M. Quigley. "Lactobacillus and Bifidobacterium in Irritable Bowel Syndrome: Symptom Responses and Relationship to Cytokine Profiles." Gastroenterology 128.3 (2005): 541-51.
6
Beausoleil, M., N. Fortier, S. Guenette, A. L'Ecuyer, M. Savoie, M. Franco, J. Lachaine, and K. Weiss. "Effect of a Fermented Milk Combining Lactobacillus Acidophilus CL1285 And Lactobacillus Caseiin the Prevention of Antibiotic-Associated Diarrhea: A Randomized, Double-Blind, Placebo-Controlled Trial." Canadian Journal of Gastroenterology 21.11 (2007): 732-36.
7
Gao, X. W., M. Mubasher, C. Y. Fang, C. Reifer, and L. E. Miller. "Dose-Response Efficacy of a Proprietary Probiotic Formula of Lactobacillus Acidophilus CL1285 and Lactobacillus Casei LBC80R for Antibiotic-Associated Diarrhea and Clostridium Difficile-Associated Diarrhea Prophylaxis in Adult Patients." American Journal of Gastroenterology 105.7 (2010): 1636-641.
8
Sampalis, J., E. Psaradellis, and E. Rampakakis. “Efficacy of BIO K+ CL1285® in the Reduction of Antibiotic-Associated Diarrhea – a Placebo Controlled Double-Blind Randomized, Multi-Center Study.” Archives of Medical Science: AMS 6.1 (2010): 56–64.
9
Johnston, B. C., S. S.y. Ma, J. Z. Goldenberg, K. Thorlund, P. O. Vandvik, M. Loeb, and G. H. Guyatt. "Probiotics for the Prevention of Clostridium Difficile -Associated Diarrhea: A Systematic Review and Meta-analysis." Annals of Internal Medicine 157.12 (2012): 878
10
Johnson, S., P.J Maziade, L. V. McFarland, W. Trick, C. Donskey, B. Currie, D. E. Low, and E. J.C Goldstein. "Is Primary Prevention of Clostridium Difficile Infection Possible with Specific Probiotics?" International Journal of Infectious Diseases 6.11 (2012): E786-792.
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